High Protein Chicken Enchilada Casserole
A bubbling high protein chicken enchilada casserole layered with shredded chicken, red enchilada sauce, black beans, and melty cheese — 50g of protein per serving with all the comfort of classic enchiladas.
Prep
15 min
Cook
35 min
Total
50 min
Servings
6
Calories
510

Ingredients
- 2 lbs boneless skinless chicken breasts
- 1 (28 oz) can red enchilada sauce
- 1 tbsp olive oil
- 1 yellow onion, diced
- 2 cloves garlic, minced
- 1 tbsp chili powder
- 2 tsp ground cumin
- 1 tsp smoked paprika
- 1 tsp kosher salt
- 1 (15 oz) can black beans, drained and rinsed
- 1 cup frozen corn kernels
- 1 (4 oz) can diced green chiles
- 10 (6-inch) corn tortillas, cut in half
- 2 cups shredded reduced-fat Mexican cheese blend
- 1/2 cup nonfat plain Greek yogurt
- 1/3 cup chopped fresh cilantro
- Lime wedges, for serving
Instructions
- 1
Place the chicken breasts in a large pot and cover with water by 1 inch. Bring to a gentle simmer and poach 15 minutes until the internal temperature reads 165°F. Transfer to a bowl and shred with two forks while warm.
- 2
Preheat the oven to 375°F and lightly grease a 9x13 baking dish.
- 3
Heat the olive oil in the same pot over medium. Add the onion and cook 3 minutes, then add the garlic, chili powder, cumin, paprika, and salt. Cook 30 seconds until fragrant.
- 4
Add the shredded chicken, black beans, corn, green chiles, and 1 cup of enchilada sauce. Stir until everything is coated and saucy.
- 5
Spread 1/2 cup of enchilada sauce in the bottom of the baking dish. Layer half the tortilla halves, half the chicken filling, 1 cup of enchilada sauce, and 3/4 cup cheese. Repeat the layers.
- 6
Top with the remaining enchilada sauce and the final 1/2 cup of cheese.
- 7
Bake uncovered 30–35 minutes until bubbly around the edges and the cheese is melted and golden in spots.
- 8
Rest 10 minutes before serving — this lets the layers set so you get clean scoops. Top each serving with a dollop of Greek yogurt, fresh cilantro, and a squeeze of lime.
Nutrition Facts
Per serving · 510 calories
protein
50g
carbs
42g
fat
15g
fiber
8g
sugar
6g
sodium
820mg
Related Recipes
More high protein and similar dishes you'll love.

High Protein Chicken Burrito Bowl
A loaded high protein chicken burrito bowl with cilantro-lime rice, black beans, charred corn salsa, and juicy seasoned chicken — 48g of protein in one meal-prep friendly bowl.

High Protein BBQ Chicken Rice Bowl
Smoky shredded BBQ chicken over fluffy rice with sweet corn, black beans, and a cool ranch drizzle — a 52g protein BBQ chicken rice bowl built for meal prep.

High Protein Southwest Chicken Salad
A loaded high protein Southwest chicken salad with smoky grilled chicken, black beans, charred corn, avocado, and a creamy cilantro-lime dressing — 50g protein in one big bowl.

High Protein Greek Yogurt Chicken Salad
Creamy high protein Greek yogurt chicken salad with shredded chicken, crisp celery, sweet grapes, and fresh dill — 42g of protein with way less fat than the deli classic.

High Protein Buffalo Chicken Dip
A creamy, lightened-up high protein buffalo chicken dip with Greek yogurt and cottage cheese — 28g of protein per serving with all the spicy, cheesy flavor of the game-day classic.

High Protein Meal Prep Chicken Bowls
Five make-ahead high protein meal prep chicken bowls with juicy seasoned chicken breast, fluffy brown rice, and roasted veggies — 46g of protein per container and ready for the whole week in under an hour.
Frequently Asked Questions
Is this casserole easier than rolling individual enchiladas?+
Way easier — you stack instead of roll, which cuts prep time in half and guarantees every layer is evenly saucy. Same flavor, none of the wrist work.
Can I use rotisserie chicken to save time?+
Yes — one 2.5 lb rotisserie chicken yields about 4 cups of shredded meat. Skip the poaching step entirely and you'll have this casserole in the oven in 15 minutes.
How much protein is in one serving?+
Each of 6 servings packs 50g of protein from the chicken breast, black beans, cheese, and Greek yogurt topping — one of the highest-protein high protein dinner recipes on RecipeNest.
Can I make it gluten-free?+
It already is — corn tortillas keep this naturally gluten-free. Double-check that your enchilada sauce is GF (most are).
Can I freeze chicken enchilada casserole?+
Yes — assemble in a freezer-safe dish, wrap tightly, and freeze unbaked up to 3 months. Thaw overnight in the fridge and bake as directed, adding 10–15 minutes.
What sides go with enchilada casserole?+
A scoop of cilantro-lime rice and a simple avocado salad. Pair with our Ground Beef Tacos rotation through the week for an all-Mexican meal prep week.

Recipe by Sarah Mitchell
Professional home cook · Tested in a real American kitchen
Get more recipes like this
Get weekly meal plans and family-friendly recipes delivered to your inbox.
You May Also Like
Hand-picked favorites from across RecipeNest.

The Best Chocolate Chip Cookies
Soft, chewy chocolate chip cookies with crisp edges and gooey centers. The only recipe you'll ever need.

The Best Moist Banana Bread
Bakery-style banana bread that's soft, moist, and packed with deep banana flavor. One bowl, no mixer, ready for the oven in 10 minutes.

Garlic Butter Chicken
Tender, golden-seared chicken bathed in a rich garlic butter pan sauce. A 20-minute restaurant-style dinner with just 6 ingredients.

Crispy Air Fryer Chicken Wings
Extra-crispy chicken wings in the air fryer — no flour, no breading, just perfectly crackly skin.