High Protein

High Protein Chicken Enchilada Casserole

By RecipeNest · High Protein

Our Chicken Enchilada Casserole is a bubbling Mexican-inspired bake with a massive 50g of protein. A healthy, easy-to-layer dinner that brings all the comfort of traditional enchiladas.

P Save to Pinterest

Prep

15 min

Cook

35 min

Total

50 min

Servings

6

Calories

510

High Protein Chicken Enchilada Casserole
AdSense — In-Content 336×280

Ingredients

  • 2 lbs boneless skinless chicken breasts
  • 1 (28 oz) can red enchilada sauce
  • 1 tbsp olive oil
  • 1 yellow onion, diced
  • 2 cloves garlic, minced
  • 1 tbsp chili powder
  • 2 tsp ground cumin
  • 1 tsp smoked paprika
  • 1 tsp kosher salt
  • 1 (15 oz) can black beans, drained and rinsed
  • 1 cup frozen corn kernels
  • 1 (4 oz) can diced green chiles
  • 10 (6-inch) corn tortillas, cut in half
  • 2 cups shredded reduced-fat Mexican cheese blend
  • 1/2 cup nonfat plain Greek yogurt
  • 1/3 cup chopped fresh cilantro
  • Lime wedges, for serving

Instructions

  1. 1

    Place the chicken breasts in a large pot and cover with water by 1 inch. Bring to a gentle simmer and poach 15 minutes until the internal temperature reads 165°F. Transfer to a bowl and shred with two forks while warm.

  2. 2

    Preheat the oven to 375°F and lightly grease a 9x13 baking dish.

  3. 3

    Heat the olive oil in the same pot over medium. Add the onion and cook 3 minutes, then add the garlic, chili powder, cumin, paprika, and salt. Cook 30 seconds until fragrant.

  4. 4

    Add the shredded chicken, black beans, corn, green chiles, and 1 cup of enchilada sauce. Stir until everything is coated and saucy.

  5. 5

    Spread 1/2 cup of enchilada sauce in the bottom of the baking dish. Layer half the tortilla halves, half the chicken filling, 1 cup of enchilada sauce, and 3/4 cup cheese. Repeat the layers.

  6. 6

    Top with the remaining enchilada sauce and the final 1/2 cup of cheese.

  7. 7

    Bake uncovered 30–35 minutes until bubbly around the edges and the cheese is melted and golden in spots.

  8. 8

    Rest 10 minutes before serving — this lets the layers set so you get clean scoops. Top each serving with a dollop of Greek yogurt, fresh cilantro, and a squeeze of lime.

Nutrition Facts

Per serving · 510 calories

protein

50g

carbs

42g

fat

15g

fiber

8g

sugar

6g

sodium

820mg

Sponsored Post Slot

More high protein and similar dishes you'll love.

High Protein Chicken Burrito Bowl
High Protein30 min

High Protein Chicken Burrito Bowl

This high protein chicken burrito bowl is the ultimate meal prep solution. Packed with 48g of protein, juicy seasoned chicken, and cilantro lime rice, it is a healthy way to stay full all day.

15 min prep·4 servings
High Protein BBQ Chicken Rice Bowl
High Protein30 min

High Protein BBQ Chicken Rice Bowl

Enjoy a smoky high protein BBQ chicken rice bowl featuring shredded chicken and a creamy ranch drizzle. With 52g of protein, it is a satisfying meal prep dinner that builds muscle.

10 min prep·4 servings
High Protein Southwest Chicken Salad
High Protein27 min

High Protein Southwest Chicken Salad

This high protein Southwest chicken salad combines smoky grilled chicken with a creamy cilantro lime dressing. It contains 50g of protein, making it an incredibly filling and healthy salad.

15 min prep·4 servings
High Protein Greek Yogurt Chicken Salad
High Protein15 min

High Protein Greek Yogurt Chicken Salad

Swap the mayo for this high protein Greek yogurt chicken salad. It is a lightened-up classic with 42g of protein that stays creamy thanks to the yogurt and fresh dill.

15 min prep·4 servings
High Protein Buffalo Chicken Dip
High Protein30 min

High Protein Buffalo Chicken Dip

Enjoy this lightened-up high protein buffalo chicken dip without the guilt. By using Greek yogurt and cottage cheese, you get 28g of protein in this spicy, cheesy favorite.

10 min prep·8 servings
High Protein Meal Prep Chicken Bowls
High Protein45 min

High Protein Meal Prep Chicken Bowls

Save time with these Meal Prep Chicken Bowls, providing 46g of protein per serving. A healthy, efficient way to prep a week of high protein lunches with seasoned chicken and roasted vegetables.

15 min prep·5 servings

Frequently Asked Questions

Is this casserole easier than rolling individual enchiladas?+

Way easier — you stack instead of roll, which cuts prep time in half and guarantees every layer is evenly saucy. Same flavor, none of the wrist work.

Can I use rotisserie chicken to save time?+

Yes — one 2.5 lb rotisserie chicken yields about 4 cups of shredded meat. Skip the poaching step entirely and you'll have this casserole in the oven in 15 minutes.

How much protein is in one serving?+

Each of 6 servings packs 50g of protein from the chicken breast, black beans, cheese, and Greek yogurt topping — one of the highest-protein high protein dinner recipes on RecipeNest.

Can I make it gluten-free?+

It already is — corn tortillas keep this naturally gluten-free. Double-check that your enchilada sauce is GF (most are).

Can I freeze chicken enchilada casserole?+

Yes — assemble in a freezer-safe dish, wrap tightly, and freeze unbaked up to 3 months. Thaw overnight in the fridge and bake as directed, adding 10–15 minutes.

What sides go with enchilada casserole?+

A scoop of cilantro-lime rice and a simple avocado salad. Pair with our Ground Beef Tacos rotation through the week for an all-Mexican meal prep week.

Sarah Mitchell

Recipe by Sarah Mitchell

Professional home cook · Tested in a real American kitchen

Get more recipes like this

Get weekly meal plans and family-friendly recipes delivered to your inbox.

You May Also Like

Hand-picked favorites from across RecipeNest.