High Protein Cottage Cheese Lasagna
A bubbly, cheesy high protein cottage cheese lasagna with lean ground turkey, blended cottage cheese, and a rich marinara — 44g of protein per slice and tastes exactly like the classic.
Prep
25 min
Cook
45 min
Total
1 hr 10 min
Servings
8
Calories
480

Ingredients
- 12 lasagna noodles (regular or no-boil)
- 1.5 lbs lean ground turkey (93% lean)
- 1 yellow onion, diced
- 4 cloves garlic, minced
- 1 tbsp olive oil
- 1 tsp Italian seasoning
- 1/2 tsp red pepper flakes
- 1 (24 oz) jar low-sugar marinara sauce
- 1 (15 oz) can crushed tomatoes
- 24 oz low-fat cottage cheese (small curd)
- 1 large egg
- 1/2 cup grated parmesan, plus more for topping
- 1/4 cup chopped fresh basil, plus leaves for garnish
- 2.5 cups shredded part-skim mozzarella
- 1 tsp kosher salt
- 1/2 tsp black pepper
Instructions
- 1
Preheat the oven to 375°F. Bring a large pot of salted water to a boil and cook the lasagna noodles 2 minutes shy of al dente. Drain and lay flat on parchment so they don't stick.
- 2
Heat the olive oil in a large skillet over medium-high. Add the onion and cook 3 minutes, then add the garlic, Italian seasoning, and red pepper flakes. Cook 30 seconds until fragrant.
- 3
Add the ground turkey and break it up with a wooden spoon. Cook 6–8 minutes until no pink remains and the bottom of the pan starts to brown — that fond is flavor.
- 4
Stir in the marinara, crushed tomatoes, 1/2 teaspoon salt, and the black pepper. Simmer 10 minutes to thicken.
- 5
Blend the cottage cheese until smooth in a food processor (about 30 seconds). This step is non-negotiable — blended cottage cheese reads as creamy ricotta. Stir in the egg, parmesan, basil, and remaining 1/2 teaspoon salt.
- 6
Spread 1 cup of meat sauce in the bottom of a 9x13 baking dish. Layer 4 noodles, half the cottage cheese mixture, 1/3 of the remaining sauce, and 3/4 cup mozzarella. Repeat the layers once more.
- 7
Top with the final 4 noodles, the remaining sauce, and the last 1 cup of mozzarella plus a sprinkle of parmesan.
- 8
Cover with foil (tent it so the cheese doesn't stick) and bake 25 minutes. Uncover and bake 15 more minutes until bubbly and deep golden on top.
- 9
Rest 15 minutes before slicing — this is what gives you clean, restaurant-style slices instead of a slumping mess. Garnish with fresh basil leaves.
Nutrition Facts
Per serving · 480 calories
protein
44g
carbs
42g
fat
16g
fiber
5g
sugar
9g
sodium
780mg
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Frequently Asked Questions
Does cottage cheese lasagna taste like the ricotta version?+
When you blend it smooth, you cannot tell the difference. Blended low-fat cottage cheese has the exact creamy, slightly tangy profile of ricotta — with about 12g more protein per cup.
Why blend the cottage cheese?+
Unblended cottage cheese leaves visible curds in every slice. A 30-second blitz transforms it into the creamy, ricotta-style filling that makes this one of the best healthy high protein meals on RecipeNest.
Can I use ground beef or chicken instead?+
Yes — 93% lean ground beef adds richer flavor, and ground chicken keeps it leaner. Macros barely change. Lean ground turkey is our pick for the best balance of flavor and 44g of protein per slice.
Can I make this lasagna ahead?+
Assemble up to 24 hours ahead, cover tightly, and refrigerate. Add 10 minutes to the covered bake time if going from cold. It also freezes beautifully — wrap unbaked, freeze up to 3 months, thaw overnight, then bake.
How do I keep my lasagna from being watery?+
Three rules: simmer the sauce 10 full minutes to reduce, drain noodles well, and let the lasagna rest 15 minutes before cutting. Skipping the rest is the #1 reason home lasagna runs.
What should I serve with high protein lasagna?+
A simple kale Caesar or our Classic Chicken Caesar Salad keeps the meal feeling like a treat without blowing the macros. Garlic green beans are another fast side.

Recipe by Sarah Mitchell
Professional home cook · Tested in a real American kitchen
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